西安医学院教案

课程 名称 教师 中药药剂学 陈程 班级 0902 专业技术职务 助教 层次 方式 讲授 本科 课时 2 Chapter Teaching material Purpos： Chapter 1 Introduction Pharmaceutics of T.C.M 1.Terms concerned 2. the selection of dosage forms 3. Property of pharmaceutics of T.C.M Content： 1、 the property and task of pharmaceutics of T.C.M 2、 Terms concerned 3、 progress of pharmaceutics of TCM 4、 the selection of dosage forms 5、 others standards Teaching method：teach。 Teaching tool ：Media Focal and difficult points： 1、the selection of dosage forms 2、Terms concerned 3、others standards Opinions of teaching and research section： （Head of the TeachingResearch Section） 2012.9.10

Content TIME 30min Chapter 1 Introduction ◆ ◆ Section1 introduction the property and task of pharmaceutics of T.C.M Property of pharmaceutics of T.C.M 1、Definition：Pharmaceutics of T.C.M is a synthetical applied branch of science which studies the theories of preparation, techniques of manufacture, methods of quality control and clinical applications of preparations of T.C.M. with modern techniques under the guidance of the theory of the T.C.M. 2. Property ◆under the guidance of the theory of the T.C.M. ◆ Contents: Pharmaceutical preparation and medicine compounding 3、Branch sciences of pharmaceutics ① industrial pharmaceutics ② physical pharmaceutics ③ biopharmaceutics ④ pharmacokinetics ⑤(clinical pharmacy) Tasks of pharmaceutics of TCM ①Terms concerned ② Dosage forms ◆ It is defined as the adequate forms of medicine in which the medicines is administrated. Section 2 History of pharmaceutics of TCM ◆ Survey of history of pharmaceutics of TCM Xia dynasty and Shang dynasty： Medicinal liquor、decoction ? war states period “The Yellow Emperor’s Internal Classic”, which is the first medical and pharmaceutical ancient codex and literature in our nation, recorded some original dosage forms: decoctions, pills, powders, plaster, “danji”）, medicinal liquors, etc., and presented their making method, administration and indication. It was supposed a precursor of pharmaceutics. ? “Treatise on Febrile and Miscellaneous Diseases” ? “Synopsis of Prescriptions of the Golden Chamber” ? In Jin Dynasty, ? “A handbook of Prescriptions for Emergencies”, ? In Tang Dynasty ? “The Newly-Revised Materia Medica”, the earliest pharmacopoeia in the world. ? In Song Dynasty, The first standard of pharmaceuticals appeared in 1080 A.D.. “The Recipes of Taipinghuimin Pharmacy” ? The theory of pharmaceutics evolved in Jin and Yuan dynasty ? Ming and Qing dynasty ? In Ming Dynasty: “Compendium of Materia Medica”, 1892 In Qing Dynasty: the formation of the Sect of Epidemic Febrile 20min Diseases ? Modern times ? progress of pharmaceutics of TCM new technology ? 1、super-fine milling ： ? 2、extration： ? （1）semi-bionic extraction method ? （2） supercritical fluid extraction method ? （3）ultrasonic wave extraction ? 3、separation technology ? （1） membrane filtration ? （2）Flocculation sedimentation ? （3）large pore resin adsorption （4）High speed centrifuge ? ? 4、concentration and drying technology ? 5、 granulating technology： ? 6、Coating ? Film coating ? 7、Solid dispersing technique ? new dosage forms ? the first generation ? the second generation ? the third generation（sustain release）、 (controlled release) ? forth generation 15min 15min ? the fifth generation Section3 classification of dosage forms 1、Classification according to physical phases 2、Dosage forms are classified by making methods: 3、 Dosage forms are classified by dispersion systems 15min 4、Dosage forms are classified by the ways by which the drugs are ? targeting preparation administered. Section 4 the selection of dosage forms ? 1、 according to the clinical requirements ? 2、 according to the property of active components. 3、 according to the biopharmaceutics and pharmacokinetics property 4、 according to manufacture facility and for convenience ? Pharmacopoeia and the standards ? 1.Pharmacopoeia ? definition of pharmacopoeia ? Pharmacopoeia is the national standard for drugs. It is compiled and promulgated by government. It is of legal authority. ? 2.Reviews of Chinese pharmacopoeia ? The first pharmacopoeia published by a government between 657-659 A.D. is “the Newly Revised Materia Medica” ? P.R.China Pharmacopoeia. (P.R.C.P.): ? Others (without legal authority): ? “Pharmacopoeia internationalis”(Ph.Int.) ? WHO：world health organization ? “European Pharmacopoeia”(Eur.Ph.) ? 3、The drug standard promulgated by The Public Health Ministry of P.R.C. ? 4、others standards （GMP）good manufacturing practice of drug （GLP）good laboratory practice of drug (GCP) good clinical practice of drug （GAP）good agricultural practice for chinese crude drugs （GSP）good supply practice ?

小结 2min 1.the property and task of pharmaceutics of T.C.M 2.Terms concerned 3.progress of pharmaceutics of TCM 4.the selection of dosage forms 复习题 3min 1.Terms concerned 2.progress of pharmaceutics of TCM 3.the selection of dosage forms 教学后记 评估：评教——征求教师和学生意见 评学——下一节课前5分钟测试 改进方法： 时间利用：